NIH; National Institutes Q = of Health COVID-19 Public health information from CDC Research information from NIH Espanol NIH staff guidance on coronavirus (NIH Only) NIH RESEARCH MATTERS March 1 2022 Use of melatonin supplements among adults Dmp& At a Glance The use of melatonin supplements by adults in the United States more than quintupled between 1999 and 2018. The findings highlight the need to better understand the term safety of melatonin use and its ability to help with certain sleep problems. rising long;