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REAL-TIME SIGNALS FROM BODY TO BRAIN HELP REGULATE SENSATION OF THIRST
Real-Time Signals from Body to Brain Help Regulate
Sensation of Thirst
Christopher Zimmerman is the 2020 Eppendorf & Science Prize for Neurobiology for discovering how the brain
estimates our need for water even before information from ingested food or fluids has entered our bloodstream. His
research reveals that; upon eating or
drinking, signals arise from the mouth and
providing "predictive" information
to brain neurons that use these
signals to satiate Or convey thirst.
Zimmerman
work demonstrates how and which activities outside of the brain contribute to
feeling thirsty, identifying
previously unknown body-to-brain pathways that work together to govern this fundamental sensation.
The prize-winning research provides an elegant neurobiological explanation for a phenomenon that each of us has
experienced many times in our lives,
said Peter Stern, senior editor at Science. The work helps explain, for example, how
we can
quickly feel thirst; how the sensation changes
meals, and why cold drinks have a thirst-quenching power:
Top
gut,
during