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REAL-TIME
GNALS FROM BodXTQ BRXIN HELP REGULATE SEMSATONOFTF RST
Real-Time Signals from Body to Brain Help Regulate
Sensation of Thirst
Christopher Zimmerman is the 2020 Eppendorf & Science Prize for Neurobiology for discovering how the brain
estimates OUI need fol water even before information from ingested food or fluids has entered our bloodstream His
research reveals that, upon eating Or
drinking, signals arise from the mouth and gut; providing "predictive" information
to brain neurons that use these
signals to satiate O1 convey thirst.
Zimmernan
work demonstrates how and which activities outside of the brain contribute to
feeling thirsty identifying
previously unknown body-to-brain pathways that work together to govern this fundamental sensation
"The prize-winning research provides an elegant neurobiological explanation for a phenomenon that each of us has
experienced many times in our lives,
said Peter Stern, senior editor at Science The work helps explain, for
example, how
we Cn)
quickly feel thirst; how the sensation changes during meals, and why cold drinks have a thirst-quenching power: